# cd /var/log/mysql
# ll
合計 134308
-rw-rw---- 1 mysql mysql 137367185 11月  7 01:20 mysql-slow.log
-rw-r----- 1 mysql mysql     22898  9月 27 01:04 mysql.log
# mv mysql-slow.log mysql-slow.log.old
# mysql -u root -p
Enter password: 
Welcome to the MySQL monitor.  Commands end with ; or \g.
Your MySQL connection id is 304599784
Server version: 5.5.27-log MySQL Community Server (GPL) by Remi

Copyright (c) 2000, 2011, Oracle and/or its affiliates. All rights reserved.

Oracle is a registered trademark of Oracle Corporation and/or its
affiliates. Other names may be trademarks of their respective
owners.

Type 'help;' or '\h' for help. Type '\c' to clear the current input statement.

mysql> flush slow logs;
Query OK, 0 rows affected (0.00 sec)

mysql> exit
Bye

# スローログ
mysql> flush slow logs;

# 一般クエリログ
mysql> flush general logs;

# バイナリログ
mysql> flush binary logs;

http://blog.inouetakuya.info/entry/20130320/1363776504